en پزشکی عمومى General medicine تحقیقی Original article <div style="text-align: justify;">​​<br> <em><strong>Background and Objective</strong></em>: Human development is influenced by genetic, environmental, and social factors whose foundation is formed from infancy and childhood. Preterm birth and low birth weight are important issues that can affect the development and threaten the public health.<span dir="RTL"></span><br> The aim of this study was to investigate the effect of early exercise interventions on gross motor skills of children with preterm birth aged 3 to 6 years.<br> <em><strong>Material and Methods</strong></em><em><strong>:</strong></em> In this Experimental study, 30 children with average (2066 &plusmn;354g) were selected from among the preterm infants (32 to 37 weeks less than 2500 g) admitted to NICU ward. They were divided into two groups (experimental group n=15 and control group n=15 children).To evaluate the gross motor skills of children, the second version of the Peabody developmental motor scale was used. The results were analyzed by SPSS using ANCOVA test (p&le;0.05).<br> <strong><em>Results</em></strong><em>:&nbsp;</em>The results of this study showed that early interventions can have a positive effect on the gross motor skills of these children and the participants in the experimental group were able to obtain higher scores than the control group after participating in the training program.<span dir="RTL"></span><br> <strong><em>Conclusion</em></strong>: The results showed that training interventions have a significant effect on both stability and locomotion skills.</div> <div> <div style="text-align: justify;"><div id="_com_1" uage="JavaScript"></div></div> </div> Premature Birth,Growth and Development,Early Medical Intervention,Locomotion, 4 12 http://goums.ac.ir/jorjanijournal/browse.php?a_code=A-10-813-1&slc_lang=en&sid=1 mousa dehghan Abghasemi@fullerton.edu 10031947532846007093 0000000160928802 No Department of Motor Development, Science and Research Branch, Islamic Azad University, Tehran, Iran abdollah ghasemi Abghasemi@fullerton.edu 10031947532846007094 0000000171136894 Yes Department of Motor Development, Science and Research Branch, Islamic Azad University, Tehran, Iran Ali Kashi ssrc.kashi@gmail.com 10031947532846007095 0000000311259125 No Associate Professor of Motor Control and Learning Department, Sport Sciences Research Institude, Tehran, Iran Elaheh Arabameri eameri@ut.ac.ir 10031947532846007096 0000000159487288 No Associate Professor of Motor Behavior, Tehran University Kayvan Molanorouzi K-mola-norouzi@iiau.ac.ir 10031947532846007097 000000031374460X No Department of sport Managment, Islamshahr Branch, Islamic Azad university, Islamshahr, Iran